| [生化制药论文]
【摘要】 为了 研究 Bel亚型的血清学特征和遗传背景，采用红细胞凝集试验检测先证者及其家庭成员红细胞上的A、B、H抗原和血清中的抗A抗体、抗B抗体，用凝集抑制试验检测唾液中的A、B、H血型物质。结果表明：先证者与其母、女儿3人确定为Bel亚型；先证者的2个妹妹确定为ABel亚型；先证者的父亲、儿子和配偶分别为A、B和B型。结论：我国人群中Bel亚型是家族遗传。
【关键词】 ABO血型 弱B抗原 Bel亚型 家系调查
Identification and Domestic Investigation of Bel Subtypes
Abstract In order to study the serological characteristics and genetic background of Bel subtypes, A, B and H antigens on the surface of red blood cells of the proband as well as his family and the antiA, antiB antibodies in their serum samples were detected by hemagglutination test; the A，B，H substances in saliva were determined by inhibitory agglutination test. The results indicatad that the proband, his mother and his daughter all were identified to be Bel phenotype; his two sisters were identified to be ABel phenotype; his father, son and spouse were identified to be A, B and B phenotype respectively. It is concluded that the Bel subtype exists as family genetic characteristics in China.
Key words ABO system； weak B antigen；Bel subtype; domestic investigation
B亚型较A亚型少见。凡红细胞上显示较弱的B特异性者，统称B亚型（或弱B）。B亚型的分类，基本上与A亚型平行［1］。国外报道……
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