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我国不同人群输血传播病毒感染调查 |
| [高血压医学论文] 【摘要】 目的 了解不同人群输血传播病毒(TTV)的感染状况。方法 采用套式PCR法检测血清标本中TTV DNA，并对其中1株TTV的部分基因序列进行了测定。结果 不同人群TTV DNA阳性率分别为：正常体检人群10.3%，献血员43.7%，吸毒者15.6%，血液透析病人54.4%，妓女65.0%，慢性丙型肝炎病人25.0%，非甲～庚型肝炎0/11。结论 TTV在各类人群中均有较高的感染率。
Detection of transfusion transmitted virus (TTV) in different populations of China
【Abstract】 Objective To investigate the prevalence of transfusion transmitted virus (TTV) in different populations of China. Methods TTV DNA was detected in sera collected from different populations by nested PCR. Partial gene of a TTV isolate was directly sequenced. Results The prevalences of TTV in various populations were as follows: 10.3% (31/301) in general population when receiving physical checkup; 43.7% (14/32) in blood donors; 15.6% (5/32) in intravenous drug addicts; 54.4% (6/11) in hemodialysis patients; 65% (13/32) in prostitutes; 25% (4/16) in patients with chronic hepatitis C. None of the 11 patients with non A-G hepatitis was detected TTV DNA. Conclusion High prevalence of TTV infection was found in different populations of China.
【Key words】 Transfusion transmitted virus (TTV) Polymerase ;chain reaction (PCR) Non A-E hepatitis virus
椐国内外报道，在急性散发性病毒性肝炎中约10%～20%为非甲～戊型肝炎，其中能检测到庚型肝炎病毒(HGV)者仅占2%～20%［1，2］，且HGV的致病性尚有争议，提示存在新型肝炎病毒的可能性。1997年底，日本学者［3］应用代表性差异分析法(Representative Differentiation Anal……
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| 投稿人：gf6h6 |
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最后编辑：647754 |
高血压医学论文 | 高血压医学论文 |
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