【摘要】  目的：观察胺碘酮治疗充血性心力衰竭伴室性心律失常临床疗效。方法：42例充血性心力衰竭伴室性心律失常患者给予口服胺碘酮治疗8周观察其临床疗效。结果：治疗两周后观察总有效率63％，治疗8周后观察总有效率78％，心功能改善明显，窦性心率HR由(97.35±16.21)/min减至(62.85±5.31)/min﹙P<0.01﹚QTc由﹙422±36﹚/ms增至(520±69)/ms(P<0.01)QTd由(64.17±9.37)/ms减至(29.42±7.03)/ms(P<0.01)。结论：胺碘酮治疗充血性心力衰竭伴室性心律失常副作用少，安全有效。

【关键词】  胺碘酮; 室性心律失常; 充血性心力衰竭

　　Clinical Effect of Amiodarone in Patients of Congestive Heart Failure with Ventricular Tachyarrhythmia

　　Abstract: Objective: The aim of the present study is to investigate the therapeutic effect of amiodarone in patients of congestive heart failure (CHF) with ventricular tachyarrhythmias. Method: 42 patients of CHF with ventricular tachyarrhythmias received oral administration of amiodarone according to required dose for 8 weeks. Result: The total effective rate were 63% after 2 weeks treatment and 78% after 8 weeks treatment. There were significant changes in the sinus rhythm ((97.35±16.21﹚/min  vs. ﹙62.85±5.31﹚/min , P<0.01), QTc intervals(﹙422±36﹚/ms vs.﹙520±69﹚/ms, P<0.01), QTd intervals(﹙422±36﹚/ms vs.﹙29.42±7.03﹚/ms,P<0.01﹚. Conclusion: Oral administration of amiodarone is safe and effective in patients of CHF with ventricular tachyarrhythmias.

　　Key words:  Amiodarone;  Ventricular tachyarrhythmias Congestive Heart failure     &nbs……